Left coronary artery
Short trunk from the left aortic sinus that divides into the anterior interventricular (LAD) and circumflex arteries, supplying most of the left ventricle.
Core anatomy
- Location
Between the pulmonary trunk and the left auricle, in the left part of the coronary sulcus.
- Origin
Left aortic sinus of the ascending aorta (above the left cusp of the aortic valve).
- Course
A short trunk (about 1–2 cm) passing between the left auricle and the pulmonary trunk before dividing. verify
- Branches
- Anterior interventricular artery (left anterior descending, LAD)
- Circumflex artery (LCx)
- Sometimes a third branch, the ramus intermedius, between the two
- Supplies
Through its branches: most of the left ventricle, the anterior two-thirds of the interventricular septum, the left atrium, and part of the right ventricle near the anterior interventricular groove. In left-dominant hearts, also the posterior septum and inferior wall.
- Termination
Bifurcates into the LAD and circumflex arteries.
Branches
Structures supplied
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Clinical correlations
Left main coronary artery disease PANCE
- Mechanism / lesion
Significant stenosis or occlusion of the left main trunk puts both the LAD and circumflex territories at risk.
- Classic presentation
Extensive anterolateral ischemia. Acute occlusion often causes cardiogenic shock or sudden death. ECG may show ST elevation in aVR with widespread ST depression. Significant left main disease is an indication for revascularization (CABG or PCI). verify
High-yield PANCE pearls
- Left main → LAD + circumflex; left main occlusion = most of the LV at risk.
- Diffuse ST depression + ST elevation in aVR → consider left main or severe multivessel disease.
- Left dominance: the posterior interventricular artery comes from the circumflex.
Imaging anatomy
- CT
Coronary CT angiography and calcium scoring. CT shows anomalous origins (e.g. left main from the right sinus).
- Ultrasound
Echo shows extensive anterior and lateral wall motion abnormalities and reduced ejection fraction.
- Key views & landmarks
- Invasive coronary angiography (RAO and LAO caudal "spider" view show the left main bifurcation)
Physical exam
- Strength / function testing
Assess for cardiogenic shock (hypotension, cool extremities, altered mental status, pulmonary edema) in suspected left main occlusion.
Self-quiz
The left coronary artery divides into which two branches?
Correct answer: B
The short left main trunk bifurcates into the anterior interventricular (LAD) and circumflex arteries. Diagonals come from the LAD; obtuse marginals from the circumflex.
Show answer
B
The short left main trunk bifurcates into the anterior interventricular (LAD) and circumflex arteries. Diagonals come from the LAD; obtuse marginals from the circumflex.
A patient with crushing chest pain is hypotensive. The ECG shows ST depression in most leads with ST elevation in aVR. Which lesion should be suspected?
Correct answer: B
Diffuse ST depression with ST elevation in aVR in an unstable patient suggests left main or severe three-vessel ischemia. This needs urgent angiography.
Show answer
B
Diffuse ST depression with ST elevation in aVR in an unstable patient suggests left main or severe three-vessel ischemia. This needs urgent angiography.
From which aortic sinus does the left coronary artery arise?
Correct answer: B
The left coronary artery arises from the left aortic sinus, the RCA from the right, and the posterior sinus has no coronary artery ("non-coronary cusp").
Show answer
B
The left coronary artery arises from the left aortic sinus, the RCA from the right, and the posterior sinus has no coronary artery ("non-coronary cusp").
The left coronary artery sometimes has a third branch arising between the LAD and circumflex. What is it called?
Correct answer: C
A ramus intermedius arises between the LAD and circumflex in some hearts. The conus and acute marginal arteries are branches of the RCA.
Show answer
C
A ramus intermedius arises between the LAD and circumflex in some hearts. The conus and acute marginal arteries are branches of the RCA.
Where does the short left main coronary trunk run before it divides?
Correct answer: D
The left coronary artery arises from the left aortic sinus and passes between the pulmonary trunk and the left auricle before dividing into the LAD and circumflex. The RCA passes between the right auricle and the pulmonary trunk.
Show answer
D
The left coronary artery arises from the left aortic sinus and passes between the pulmonary trunk and the left auricle before dividing into the LAD and circumflex. The RCA passes between the right auricle and the pulmonary trunk.