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Sudden aphasia and arm weakness

A 68-year-old right-handed man with atrial fibrillation suddenly develops weakness of the right face and arm and can't find his words. His wife last saw him well an hour ago.

Step 1 of 4

Which arterial territory is most likely affected?

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E

Contralateral face and arm weakness with aphasia (dominant hemisphere) is a left MCA stroke. ACA strokes affect the leg more than the arm; PCA strokes cause a homonymous hemianopia (see cerebral arteries (ACA, MCA, PCA)).

Step 2 of 4

Which way are his eyes most likely to deviate?

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B

In a hemispheric stroke the eyes deviate toward the lesion, away from the weak side.

Step 3 of 4

Which test comes first?

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B

A noncontrast CT comes first because hemorrhage must be excluded before thrombolysis. Check the glucose too.

Step 4 of 4

The CT shows no hemorrhage. His blood pressure is 170/95 mm Hg and he has no contraindications.

What is the most appropriate treatment?

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C

He is within 4.5 hours of last known well and his BP is below 185/110, so IV thrombolysis is indicated. If CT angiography shows a large vessel occlusion, mechanical thrombectomy is added.

Key points

  • Face and arm > leg + aphasia → left (dominant) MCA.
  • Eyes look toward the lesion in hemispheric stroke.
  • Noncontrast CT first; IV thrombolysis within 4.5 h if BP < 185/110.

Study: Cerebral arteries (ACA, MCA, PCA), Circle of Willis, Internal capsule

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